The inheritance of certain mutations of BRCA1 can make it much mo...

Question

The inheritance of certain mutations of BRCA1 can make it much more likely that a woman will develop breast or ovarian cancer in her lifetime.

Can you say with certainty that a woman inheriting a mutation of BRCA1 will definitely develop breast or ovarian cancer in her lifetime? Why or why not?

Accepted Answer

Hi, everyone. Here's our next question. Women with breast cancer in the past can have an increased risk of ovarian cancer in the future. Which of the following statements is true. Choice. A by the age of 7100% of women with a BRC A one or BRC A two mutation will develop ovarian cancer. Choice B by the age of 7100% of women with a BRC A one or BRC two mutation mutation will not develop ovarian cancer. Choice C by the age of 70 30% of women who have a BRC A one or BRC A two mutation will develop ovarian cancer or choice D none of the above. Well, we can pretty easily eliminate two of these questions. Uh Choice two of these answers. Excuse me. Choice A which states that by age 7100% of women with these mutations will develop ovarian cancer, you almost never see things like that where you see 100% of people developing something. So that would be a pretty good clue. Even if you didn't remember that this is incorrect and indeed choice A is not correct. That is not the correct statistic. That is the same with choice B which says that by the age of 7100% of people with these mutations will not develop ovarian cancer. That would be highly unlikely. Given that, hopefully, we recall that those BRC A mutations are associated with increased risk of both breast and ovarian cancer. So we can then eliminate choice de none of the above right away. And again, even if we couldn't remember that statistic, we've got just one choice left. Choice C by the age of 70 30% of women who have a BRC A one or BRC A two mutation will develop ovarian cancer. So that to C is going to be our correct answer here. See you in the next video.

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The inheritance of certain mutations of BRCA1 can make it much more likely that a woman will develop breast or ovarian cancer in her lifetime. Can you say with certainty that a woman inheriting a mutation of BRCA1 will definitely develop breast or ovarian cancer in her lifetime? Why or why not?