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Ch.3 - Chemical Reactions and Reaction Stoichiometry
Chapter 3, Problem 107

Viridicatumtoxin B, C30H31NO10, is a natural antibiotic compound. It requires a synthesis of 12 steps in the laboratory. Assuming all steps have equivalent yields of 85%, which is the final percent yield of the total synthesis?

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1
Identify that the problem involves calculating the overall percent yield of a multi-step synthesis, where each step has an equivalent yield of 85%.
Recall that the overall yield of a multi-step process is the product of the yields of each individual step.
Express the yield of each step as a decimal: 85% becomes 0.85.
Since there are 12 steps, raise the yield of one step to the power of 12: \((0.85)^{12}\).
Convert the result back to a percentage by multiplying by 100 to find the final percent yield of the total synthesis.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Percent Yield

Percent yield is a measure of the efficiency of a chemical reaction, calculated as the ratio of the actual yield to the theoretical yield, multiplied by 100. It indicates how much product is obtained from a reaction compared to the maximum possible amount, helping chemists assess the effectiveness of their synthetic processes.
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Sequential Reactions

In synthetic chemistry, sequential reactions refer to a series of chemical transformations where the product of one reaction serves as the reactant for the next. Each step can affect the overall yield, as the final product yield is influenced by the yields of all preceding steps, necessitating careful calculation of cumulative effects.
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Multiplicative Yield Calculation

When dealing with multiple steps in a synthesis, the overall yield is calculated by multiplying the yields of each individual step. For example, if each step has a yield of 85%, the final yield is determined by raising the yield to the power of the number of steps, reflecting the compounding effect of losses at each stage.
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Related Practice
Textbook Question

A mixture of N21g2 and H21g2 reacts in a closed container to form ammonia, NH31g2. The reaction ceases before either reactant has been totally consumed. At this stage 3.0 mol N2, 3.0 mol H2, and 3.0 mol NH3 are present. How many moles of N2 and H2 were present originally?

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Textbook Question

A mixture containing KClO3, K2CO3, KHCO3, and KCl was heated, producing CO2, O2, and H2O gases according to the following equations: 2 KClO31s2¡2 KCl1s2 + 3 O21g2 2 KHCO31s2¡K2O1s2 + H2O1g2 + 2 CO21g2 K2CO31s2¡K2O1s2 + CO21g2 The KCl does not react under the conditions of the reaction. If 100.0 g of the mixture produces 1.80 g of H2O, 13.20 g of CO2, and 4.00 g of O2, what was the composition of the original mixture? (Assume complete decomposition of the mixture.) How many grams of K2CO3 were in the original mixture?

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Open Question
Boron nitride, BN, is an electrical insulator with remarkable thermal and chemical stability. Its density is 2.1 g/cm3. It can be made by reacting boric acid, H3BO3, with ammonia. The other product of the reaction is water. (b) If you made 225 g of boric acid react with 150 g of ammonia, what mass of BN could you make? (d) One application of BN is as a thin film for electrical insulation. If you take the mass of BN from part (b) and make a 0.4 mm thin film from it, what area, in cm2, would it cover?
Textbook Question

(b) Because atoms are spherical, they cannot occupy all of the space of the cube. The silver atoms pack in the solid in such a way that 74% of the volume of the solid is actually filled with the silver atoms. Calculate the volume of a single silver atom.

Textbook Question

Burning acetylene in oxygen can produce three different carbon-containing products: soot (very fine particles of graphite), CO(g), and CO2(g). (c) Why, when the oxygen supply is adequate, is CO2(g) the predominant carbon-containing product of the combustion of acetylene?

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Open Question
Section 2.9 introduced the idea of structural isomerism, with 1-propanol and 2-propanol as examples. Determine which of these properties would distinguish these two substances: (a) boiling point, (b) combustion analysis results, (c) molecular weight, (d) density at a given temperature and pressure. You can check on the properties of these two compounds in Wolfram Alpha (http://www.wolframalpha.com/) or the CRC Handbook of Chemistry and Physics.