Butyric acid is responsible for the foul smell of rancid butter. The pKa of butyric acid is 4.84. (a) Calculate the pKb for the butyrate ion.
Ritalin is the trade name of a drug, methylphenidate, used
to treat attention-deficit/hyperactivity disorder in young
adults. The chemical structure of methylphenidate is

(a) Is Ritalin an acid or a base? An electrolyte or a nonelectrolyte?


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Key Concepts
Acids and Bases
Electrolytes
Chemical Structure and Functional Groups
Butyric acid is responsible for the foul smell of rancid butter. The pKa of butyric acid is 4.84. (b) Calculate the pH of a 0.050 M solution of butyric acid.
Butyric acid is responsible for the foul smell of rancid butter. The pKa of butyric acid is 4.84. (c) Calculate the pH of a 0.050 M solution of sodium butyrate.
The following observations are made about a diprotic acid H2A: (i) A 0.10 M solution of H2A has pH = 3.30. (ii) A 0.10 M solution of the salt NaHA is acidic. Which of the following could be the value of pKa2 for H2A: (i) 3.22, (ii) 5.30, (iii) 7.47, or (iv) 9.82?
The amino acid glycine 1H2N¬CH2¬COOH2 can participate in the following equilibria in water: H2N¬CH2¬COOH + H2OΔ H2N¬CH2¬COO- + H3O+ Ka = 4.3 * 10-3 H2N¬CH2¬COOH + H2OΔ+H3N¬CH2¬COOH + OH- Kb = 6.0 * 10-5 (a) Use the values of Ka and Kb to estimate the equilibrium constant for the intramolecular proton transfer to form a zwitterion: H2N¬CH2¬COOH Δ +H3N¬CH2¬COO-