Chapter 46, Problem 10
The BMI z-score is a relative measure of body mass index (BMI) that takes into account age. Higher values represent heavier individuals for a given height. The table here shows the BMI z-score of pre- and post-pubertal girls at three ages. Which of the following conclusions can you draw from the data? a. At a given age, there are more girls with low BMI z-scores than with high BMI z-scores. b. At a given age, girls with high BMI z-scores are more likely to have begun puberty than girls with low BMI z-scores. c. Girls 11, 12, and 13 years of age are equally likely to have begun puberty. d. There is no relationship between BMI z-score and age of beginning puberty.
Video transcript
Imagine a situation in which a morphogen has its source at the posterior end of a Drosophila embryo. Every 100 µm from the posterior pole, the morphogen concentration decreases by half. If a cell required 1/16th the amount of morphogen found at the posterior pole to form part of a leg, how far from the posterior pole would the leg form? a. 100 μm b. 160 μm c. 400 μm d. 1600 μm
Propose an experiment to test the hypothesis that cells from only one region of a frog blastula form the ectoderm. What results from this experiment would support this hypothesis?
Some stickleback fish develop protective spines, and other stickleback fish are spineless. Spine development is controlled by the expression of a gene known as Pitx1. The spineless phenotype is due to a mutation in Pitx1 that results in no expression of Pitx1 during development in regions where spines would otherwise form. When scientists compared the Pitx1 coding sequence in spined and spineless fish, they found this sequence was the same in both types of fish. Propose plausible hypotheses for the location of this mutation and for how it alters spine development.
Type I diabetes is a form of diabetes that is due to the loss of insulin-producing cells of the pancreas. The potential of stem cells—in particular, induced pluripotent stem (iPS) cells—for therapy has gotten a lot of press. What are iPS cells? a. cells taken from early human embryos b. cells taken from the pancreas of people without diabetes c. cells derived by de-differentiating specialized adult cells d. cells derived by differentiating pancreas precursor cells
In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Which of the following is the most effective form of contraception? a. condom b. diaphragm c. withdrawal d. the pill
Type I diabetes is a form of diabetes that is due to the loss of insulin-producing cells of the pancreas. The potential of stem cells—in particular, induced pluripotent stem (iPS) cells—for therapy has gotten a lot of press. If researchers were attempting to stimulate the differentiation of iPS cells, which of the following would they most likely add to the cell-culture medium (the liquid surrounding the cells)? a. activin A, an extracellular signal protein b. Sox-2, a transcription factor active in early development c. Grb-2, an intracellular signal transduction protein d. lactase, an enzyme that catalyzes the breakdown of lactose