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Ch. 47 - Animal Reproduction and Development

Chapter 46, Problem 14

In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Use the information in the graph to explain how the pill affects each of the following: (a) maturation of a follicle, (b) thickening of the uterine lining during the follicular phase, (c) probability of ovulation, and (d) volume of menstrual fluid.

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Welcome back. Here's the next question. Which of the following is not a function of progesterone. Well let's look through our answer choices here. Choice A says. It acts as a major birth control pill. Well this is a function of progesterone will say true here, so not our answer. Um Progesterone inhibits secretion of LH, LH and FSH. Which are necessary for the maturation of the follicle and then ovulation. So because it inhibits their secretion, it prevents ovulation and therefore can be used as a birth control pill. Choice B says it causes maximum thickening of the uterine wall. This is true. This is a function of progesterone. So not our answer here that causes uterine endometrium proliferation um creating that thick lining for the of the uterus to prepare it for implantation. So not our answer here. And finally, Choice D. Says it causes ovulation. Well this is not a function of progesterone and therefore this is our answer. It is the surgeon LH that causes ovulation. So that's not a function of progesterone. Again, our answer is Choice D causes ovulation. Not a function of progesterone. See you in the next video
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Textbook Question

In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Use your knowledge of the hormonal regulation of reproduction to predict the effect of a daily synthetic progesterone pill on (a) pituitary secretion of LH and FSH, and (b) ovarian secretion of estradiol and progesterone.

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Textbook Question

In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Scientists confirmed the pill's mechanism of action by measuring plasma hormone levels in women before and after they went on the pill (* means P<0.05, ** means P<0.01, and *** means P<0.001). Do the data shown here support the hypothesis that the pill affects hormonal signaling?

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Textbook Question

In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Use Table 47.2 to compare and contrast the mechanisms of action of emergency contraception and mifepristone to that of the pill. Which methods act as contraception and which act to terminate a pregnancy? Explain.

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Textbook Question

In the 1960s, the U.S. Food and Drug Administration approved a contraceptive that allowed women to plan desired pregnancies and prevent unwanted pregnancies. Oral hormonal contraception ('the pill') uses synthetic hormones similar in structure to progesterone and/or estradiol. What is the pill's mechanism of action? Imagine that four different contraceptives are under development. One blocks ovulation, one blocks fertilization, one blocks cleavage, and one blocks implantation. In the United States, which contraceptive is likely to be the least controversial to bring to market? Why?

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