Skip to main content
Ch. 19 - Control of Gene Expression in Eukaryotes

Chapter 18, Problem 8

Predict how a mutation that caused continuous production of active p53 would affect the cell.

Verified Solution
Video duration:
1m
This video solution was recommended by our tutors as helpful for the problem above.
Was this helpful?

Video transcript

Hello everyone here we have a question asking us which one is not true about the P gene. It is the most important tumor suppressor. This is correct. It plays a key role in the cellular response to DNA damage be it acts primarily at the G. One checkpoint. This is correct. It blocks the cell cycle at G. One in response to damage D. N. A. See it activates repair enzymes. This is correct. This happens when a sales D. N. A. Is damaged. It halts the cell cycle at the G. One checkpoint by by triggering the production of cell cycle inhibitors and this pause buys time for DNA repair. So C. Is correct. D P 53 is often more functional in cancer cells than normal cells. This is incorrect. As the P 53 suppresses cancer. Therefore, in cancer cells, P 53 is often missing nonfunctional or less active. So our correct answer is D. P- 53 is not often more functional in cancer cells than normal cells. Thank you for watching. Bye.
Related Practice
Textbook Question

Compare and contrast the items in each pair: (a) enhancers and the E. coli CAP binding site

216
views
Textbook Question

Compare and contrast the items in each pair: (b) promoter-proximal elements and the operator of the lac operon

254
views
Textbook Question

Compare and contrast the items in each pair: (c) general transcription factors and sigma.

267
views
Textbook Question

In the follow-up work to the experiment shown in Figure 19.6, the researchers used a technique that allowed them to see if two DNA sequences are in close physical proximity (association). They applied this method to examine how often an enhancer and the core promoter of the Hnf4a regulatory gene were near each other. A logical prediction is that compared with rats born to mothers fed a healthy diet, the Hnf4a gene in rats born to mothers fed a protein-poor diet would a. show no difference in how often the promoter and enhancer associated. b. never show any promoter–enhancer association. c. show a lower frequency of promoter–enhancer association. d. show a higher frequency of promoter–enhancer association.

401
views
Textbook Question

One hypothesis for differences between humans and chimpanzees involves differences in gene regulation. A study using RNA-seq showed that the overall patterns of gene expression were similar in the liver and blood of the two species, but the expression patterns were strikingly different in the brain. How do these results relate to the hypothesis?

454
views
Textbook Question

The Hawaiian bobtail squid (Euprymna scolopes) is able to glow from luminescent Vibrio fischeri bacteria held in its light organs. As it swims at night near the ocean surface, it adjusts the amount of light visible to predators below to match the light from the stars and moon. Predators have difficulty seeing the illuminated squid against the night sky. The bacteria glow in response to a molecule that regulates expression of genes involved in light-producing chemical reactions. The regulator controls production of the genes' mRNA. Therefore, the light-producing genes are under a. transcriptional control. b. translational control. c. post-translational control. d. negative control.

272
views