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Ch. 18 - Control of Gene Expression in Bacteria
Chapter 17, Problem 1

Why are the genes involved in lactose metabolism considered to be an operon? a. They occupy adjacent locations on the E. coli chromosome. b. They have a similar function. c. They are all required for normal cell function. d. They are all controlled by the same promoter.

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The genes involved in lactose metabolism are considered to be an operon because they are all controlled by the same promoter. An operon is a functioning unit of genomic DNA containing a cluster of genes under the control of a single promoter. In this case, the genes involved in lactose metabolism are grouped together and regulated as a single unit, which allows the cell to efficiently manage the metabolic process. Therefore, the correct answer is option d.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Operon Structure

An operon is a cluster of genes that are transcribed together as a single mRNA molecule, typically under the control of a single promoter. This arrangement allows for coordinated regulation of genes that encode proteins with related functions, facilitating efficient gene expression in response to environmental changes.
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Structure of an Operon

Gene Regulation

Gene regulation refers to the mechanisms that control the expression of genes, ensuring that the right genes are expressed at the right times. In the case of operons, regulatory elements such as promoters and operators play crucial roles in turning genes on or off in response to specific signals, such as the presence of lactose in the environment.
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Introduction to Regulation of Gene Expression

Lactose Metabolism in E. coli

In E. coli, lactose metabolism involves several genes, including lacZ, lacY, and lacA, which are responsible for the breakdown and transport of lactose. These genes are organized in the lac operon, allowing the bacterium to efficiently utilize lactose as an energy source when glucose is scarce, demonstrating the operon's role in metabolic adaptation.
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