The primary cause of death from αα-amanitin poisoning is liver failure. Suppose a physician informs you that liver cells die because their rate of protein production falls below a level needed to maintain active metabolism. Given that αα-amanitin is an inhibitor of transcription, you wonder if this information is correct. Propose an experiment to determine whether the toxin also has an effect on protein synthesis.

Video transcript

Hello everyone. And in today's video we have the following problem. So alpha amenity is a tax in which acts as an irreversible inhibitor of RNA polymerase, identify which process it would inhibit. So before we jump into the question remember that if the taxing is acting as an inhibitor of RNA polymerase, it is going to inhibit RNA synthesis. So now that we know this, let's jump into our answer choices so that we can solve this question to answer choice. A DNA replication recall from previous videos that DNA replication involves the creation of DNA from more DNA here. RNA is not at all involved. So we're going to counsel as well because the toxin will not directly affect this process. Then we have RNA processing. Well now we do have RNA here. However, these RNA processing process involves the modification of already created M. RNA. Since we're not synthesizing new R. N. A. This process will not be affected because RNA polymerase is not at all involved in the process of RNA processing. So we're going to counsel is out as well. Then we have answer choice. The translation and translation involves the transformation of M. RNA into proteins. He here again we don't have RNA polymerase here because we already have the MRNA in hand here we have rival zones creating this process or just undergoing this process. So this will also be an incorrect answer choice and finally we have answer choice B transcription. And this is the process of transforming DNA into RNA. And this process is done by RNA polymerase. So if the taxing is inhibiting RNA polymerase, this process will definitely be affected. So we're going to highlight an answer choice B transcription as a final answer to our question. I really hope this video helped you, and I hope to see you on the next one.