Skip to main content
Ch. 16+17 - Transcription, RNA Processing, and Translation

Chapter 16, Problem 13

A small portion of the human transport protein amino acid sequence is shown here. The upper sequence is associated with darker skin, and the lower sequence is associated with lighter skin. What DNA base-pair change created the light-skin form of the human protein from the gene that coded for the dark-skin form?

Verified Solution
Video duration:
1m
This video solution was recommended by our tutors as helpful for the problem above.
Was this helpful?

Video transcript

Hello everyone here we have a question telling us that a green parakeet gave birth to five young birds, four of which were green and one of which was yellow. The researcher determined the amino acid sequence for both enzymes responsible for green and yellow pigment production and found the following result. Green A L A G L Y V A L A L A P R O T H R G L Y L E. U. And yellow A L A G L Y V A L A L A T H R th R G L Y L E. U. And our goal here is to identify which DNA base pair change resulted in the L. Pillard parakeet. So if we look at these, we see that a P. R. O. It's changed to a thr This means that there must have been altered from A C. In the first position to an A. In the first position. The base pair change therefore must have been from a C. G. Base pair change to an A. T. Base pair, change in the D. N. A. Coding for the first position of the code on. So our answer here is BC. G 2 80. Thank you for watching. Bye.
Related Practice
Textbook Question

Investigators examined the expression of transporter mRNA and protein produced in zebrafish homozygous for each of the alleles and obtained the results summarized here (+ = present, −= absent). Does the allele associated with light color appear to be altering transcription or translation? Why?

291
views
Textbook Question

α-Amanitin inhibits transcription by binding inside an RNA polymerase to a region other than the active site that catalyzes addition of a nucleotide to the RNA chain. Based on the model of RNA polymerase shown in Figure 17.3, predict how the toxin might function to inhibit transcription.

937
views
Textbook Question

Toxins like αα-amanitin are used for research in much the same way as null mutants (Chapter 16)—to disrupt a process and see what happens when it no longer works. Researchers examined the ability of αα-amanitin to inhibit different RNA polymerases. They purified RNA polymerases I, II, and III from rat liver, incubated the enzymes with different concentrations of αα-amanitin, and then tested their activity. The results of this experiment are shown here. These findings suggest that cells treated with αα-amanitin will have a reduced level of: a. tRNAs b. rRNAs c. snRNAs d. mRNAs

692
views
Textbook Question

Researchers compared the amino acid sequences of the transport protein in zebrafish, puffer fish, mice, and humans. They found many stretches with identical sequences in all four species. Does this mean that the corresponding mRNA base sequences are also the same in these four species? Explain why or why not.

665
views
Textbook Question

If you wanted to use αα-amanitin to shut down 95 percent of transcription by RNA polymerase II, roughly what concentration of αα-amanitin would you use? Note that the scale on the x-axis of the graph in Question 13 is logarithmic rather than linear, so that each tick mark shows a tenfold higher concentration.

764
views
Textbook Question

Biologists have investigated how fast pre-mRNA splicing occurs by treating cells with a toxin that blocks the production of new pre-mRNAs, then following the rate of splicing of the pre-mRNAs that were transcribed before adding the toxin. Why is addition of a toxin important in this study?

317
views