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Ch. 45 - Hormones and the Endocrine System
Chapter 45, Problem 5

What do steroid and peptide hormones typically have in common? a. their solubility in cell membranes b. their requirement for travel through the bloodstream c. the location of their receptors d. their reliance on signal transduction in the cell

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Hormone Structure and Solubility

Steroid hormones are lipid-soluble and can easily pass through cell membranes, while peptide hormones are water-soluble and cannot. This difference in solubility affects how each type of hormone interacts with target cells and their receptors.
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Transport in the Bloodstream

Both steroid and peptide hormones require transport mechanisms to travel through the bloodstream. Steroid hormones often bind to carrier proteins due to their lipophilic nature, while peptide hormones circulate freely in the blood due to their hydrophilic properties.
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Receptor Location and Signal Transduction

Steroid hormones typically bind to intracellular receptors, leading to direct gene regulation, while peptide hormones bind to receptors on the cell surface, initiating signal transduction pathways. This distinction is crucial for understanding how each hormone exerts its effects on target cells.
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Related Practice
Textbook Question

The hypothalamus a. synthesizes all of the hormones produced by the pituitary gland. b. influences the function of only one lobe of the pituitary gland. c. produces only inhibitory hormones. d. regulates both reproduction and body temperature.

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Textbook Question

Growth factors are local regulators that a. are produced by the anterior pituitary. b. are modified fatty acids that stimulate bone and cartilage growth. c. are found on the surface of cancer cells and stimulate abnormal cell division. d. bind to cell-surface receptors and stimulate growth and development of target cells.

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Textbook Question

Which hormone is correctly paired with its action? (A) oxytocin—stimulates uterine contractions during childbirth (B) thyroxine—inhibits metabolic processes (C) ACTH—inhibits the release of glucocorticoids by the adrenal cortex (D) melatonin—raises blood calcium level

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Textbook Question

Which of the following is the most likely explanation for hypothyroidism in a patient whose iodine level is normal? a. greater production of T3 than of T4 b. hyposecretion of TSH c. hypersecretion of MSH d. a decrease in the thyroid secretion of calcitonin

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Textbook Question

The relationship between the insect hormones ecdysteroid and PTTH is an example of a. an interaction of the endocrine and nervous systems. b. homeostasis achieved by positive feedback. c. homeostasis maintained by antagonistic hormones. d. competitive inhibition of a hormone receptor.

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Textbook Question

DRAW IT In mammals, the production of the hormone IGF-1 by the liver is controlled by growth hormone (GH) and GH-releasing hormone. Draw a simple sketch of this pathway, including glands, tissues, hormones, routes for hormone movement, and effects.

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