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Ch. 18 - Regulation of Gene Expression
Chapter 18, Problem 8

Which of the following statements about the DNA in one of your brain cells is true? a. Most of the DNA codes for protein. b. The majority of genes are likely to be transcribed. c. It is the same as the DNA in one of your liver cells. d. Each gene lies immediately adjacent to an enhancer.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Gene Expression

Gene expression is the process by which information from a gene is used to synthesize functional gene products, typically proteins. In eukaryotic cells, this involves transcription of DNA into messenger RNA (mRNA), followed by translation into proteins. Not all genes are expressed in every cell type, which is why different cells, like brain and liver cells, can have distinct functions despite having the same DNA.
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Genomic DNA

Genomic DNA refers to the complete set of DNA, including all of its genes, present in an organism. In humans, nearly all cells contain the same genomic DNA, meaning that the DNA in a brain cell is essentially identical to that in a liver cell. However, the expression of specific genes varies between cell types, leading to their specialized functions.
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Enhancers and Gene Regulation

Enhancers are regulatory DNA sequences that can increase the likelihood of transcription of specific genes. They can be located far from the gene they regulate and interact with transcription factors to enhance gene expression. While not every gene is immediately adjacent to an enhancer, these elements play a crucial role in the precise regulation of gene expression in different cell types.
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Related Practice
Textbook Question

Which of the following is an example of post-transcriptional control of gene expression? a. the addition of methyl groups to cytosine bases of DNA b. the binding of transcription factors to a promoter c. the removal of introns and alternative splicing of exons d. gene amplification contributing to cancer

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Textbook Question

What would occur if the repressor of an inducible operon were mutated so it could not bind the operator? a. irreversible binding of the repressor to the promoter b. reduced transcription of the operon's genes c. buildup of a substrate for the pathway controlled by the operon d. continuous transcription of the operon's genes

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Textbook Question

Absence of bicoid mRNA from a Drosophila egg leads to the absence of anterior larval body parts and mirror-image duplication of posterior parts. This is evidence that the product of the bicoid gene a. normally leads to formation of head structures. b. normally leads to formation of tail structures. c. is transcribed in the early embryo. d. is a protein present in all head structures.

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Textbook Question

Within a cell, the amount of protein made using a given mRNA molecule depends partly on a. the degree of DNA methylation. b. the rate at which the mRNA is degraded. c. the number of introns present in the mRNA. d. the types of ribosomes present in the cytoplasm.

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Textbook Question

Proto-oncogenes can change into oncogenes that cause cancer. Which of the following best explains the presence of these potential time bombs in eukaryotic cells? a. Proto-oncogenes first arose from viral infections. b. Proto-oncogenes are mutant versions of normal genes. c. Proto-oncogenes are genetic 'junk.' d. Proto-oncogenes normally help regulate cell division.

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