In this video, we're going to introduce the origin of DNA replication or just the origin of replication. And so DNA replication actually begins at a specific set of DNA sequences that are collectively referred to as the Origin of Replication, or just the ori for short. And so it turns out that prokaryotic cells have a small circular chromosome, and these small circular chromosomes of prokaryotic organisms have just one single origin of replication on their chromosome. Whereas eukaryotic organisms have larger linear chromosomes, and these larger linear chromosomes of eukaryotes actually have multiple origins of replication. In some cases, they can have up to 100 origins of replication or more. And so if we take a look at our image down below, notice on the left-hand side over here, what we're showing you is prokaryotic DNA replication, and on the right-hand side over here, what we're showing you is eukaryotic DNA replication. And what you'll notice is that the chromosome of prokaryotes is circular, and the circular chromosome of prokaryotes only has just one single origin of replication. One origin of replication. Now if we take a look over here at the eukaryotic chromosome, notice that its chromosome is linear, and the linear chromosome actually has 2 origins of replication in this image, but again they can have many origins of replication, so multiple origins of replication. And so what you'll see here is that the darker blue molecules represent the old original parental DNA strands, and, as DNA replication proceeds, it's going to occur and begin at this origin of replication. And so what you'll notice here in this image is that the new DNA strands are, in the light blue color, and of course, these little pink structures are representing RNA primers, which we're going to talk more about the functions of these RNA primers, as we move forward in our course. But the point here is that the origin of replication is where DNA replication is going to begin the process. And so, you can see over here, DNA replication is going to begin and proceed. And so, this here concludes our brief introduction to the origin of replication, this set of DNA sequences that marks the beginning of DNA replication. And we'll be able to talk more and more about DNA replication as we move forward in our course. So I'll see you all in our next video.
Table of contents
- 1. Introduction to Biology2h 40m
- 2. Chemistry3h 40m
- 3. Water1h 26m
- 4. Biomolecules2h 23m
- 5. Cell Components2h 26m
- 6. The Membrane2h 31m
- 7. Energy and Metabolism2h 0m
- 8. Respiration2h 40m
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- 10. Cell Signaling59m
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- 13. Mendelian Genetics4h 44m
- Introduction to Mendel's Experiments7m
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- Epistasis7m
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- Pedigrees6m
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- Sex-Linked Inheritance43m
- X-Inactivation9m
- 14. DNA Synthesis2h 27m
- 15. Gene Expression3h 20m
- 16. Regulation of Expression3h 31m
- Introduction to Regulation of Gene Expression13m
- Prokaryotic Gene Regulation via Operons27m
- The Lac Operon21m
- Glucose's Impact on Lac Operon25m
- The Trp Operon20m
- Review of the Lac Operon & Trp Operon11m
- Introduction to Eukaryotic Gene Regulation9m
- Eukaryotic Chromatin Modifications16m
- Eukaryotic Transcriptional Control22m
- Eukaryotic Post-Transcriptional Regulation28m
- Eukaryotic Post-Translational Regulation13m
- 17. Viruses37m
- 18. Biotechnology2h 58m
- 19. Genomics17m
- 20. Development1h 5m
- 21. Evolution3h 1m
- 22. Evolution of Populations3h 52m
- 23. Speciation1h 37m
- 24. History of Life on Earth2h 6m
- 25. Phylogeny2h 31m
- 26. Prokaryotes4h 59m
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- 30. Overview of Animals34m
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- 42. Osmoregulation and Excretion50m
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- 49. Animal Behavior28m
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- Life History12m
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- Introduction to Population Growth Models22m
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- r/K Selection10m
- The Human Population22m
- 51. Community Ecology2h 46m
- Introduction to Community Ecology2m
- Introduction to Community Interactions9m
- Community Interactions: Competition (-/-)38m
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- Community Interactions: Mutualism (+/+) & Commensalism (+/0)9m
- Community Structure35m
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- Geographic Impact on Communities21m
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- 53. Conservation Biology24m
14. DNA Synthesis
Introduction to DNA Replication
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Introduction to DNA Replication practice set
