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Ch. 26 Fluid, Electrolyte, and Acid-Base Balance
Chapter 25, Problem 13

Name the body fluid compartments, noting their locations and the approximate fluid volume in each.

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Identify the two main body fluid compartments: intracellular fluid (ICF) and extracellular fluid (ECF).
Understand that the intracellular fluid (ICF) is the fluid within cells, making up about 2/3 of the total body water.
Recognize that the extracellular fluid (ECF) is the fluid outside cells, accounting for about 1/3 of the total body water.
Divide the extracellular fluid (ECF) into two sub-compartments: interstitial fluid and plasma. Interstitial fluid surrounds tissue cells, while plasma is the liquid component of blood.
Note the approximate fluid volumes: Intracellular fluid (ICF) is about 25 liters, interstitial fluid is about 12 liters, and plasma is about 3 liters in an average adult human.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Body Fluid Compartments

The human body is divided into two main fluid compartments: intracellular fluid (ICF) and extracellular fluid (ECF). ICF is the fluid within cells, making up about 60% of total body water, while ECF is found outside cells, comprising about 40%. ECF is further divided into interstitial fluid and plasma, which are crucial for transporting nutrients and waste.
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Intracellular Fluid (ICF)

Intracellular fluid refers to the fluid contained within the cells of the body. It accounts for approximately 25 liters in an average adult, representing about two-thirds of total body water. This fluid is vital for cellular processes, including metabolism, nutrient transport, and waste removal, and is rich in potassium and phosphate ions.
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Extracellular Fluid (ECF)

Extracellular fluid is the fluid outside of cells, totaling about 15 liters in an average adult. It includes interstitial fluid, which bathes the cells, and plasma, the liquid component of blood. ECF plays a critical role in maintaining homeostasis, facilitating communication between cells, and transporting substances throughout the body.
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