Here are the essential concepts you must grasp in order to answer the question correctly.
Basophils
Basophils are a type of white blood cell that play a crucial role in the immune response, particularly in allergic reactions. They release histamine and other inflammatory mediators when activated, contributing to the inflammatory process. Their presence is essential for the body's defense against pathogens and in the modulation of allergic responses.
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Histamine
Histamine is a chemical messenger released by basophils and mast cells during immune responses. It is involved in local immune responses and causes blood vessels to dilate and become more permeable, leading to inflammation and the classic symptoms of allergies. Understanding histamine's role is vital for grasping how the body reacts to allergens and pathogens.
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Inflammatory Response
The inflammatory response is a biological reaction to harmful stimuli, such as pathogens or injury. It involves the activation of immune cells, including basophils, and the release of various chemicals, including histamine, to promote healing and fight infection. This process is essential for protecting the body but can also lead to symptoms associated with allergies and chronic inflammation.
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Damaging Effects of the Inflammatory Response