Which of the following is not a role of TH cells?

a. Stimulation of macrophages

b. Activation of naïve TC cells

c. Stimulation of naïve B cells

d. Stimulation of clonal selection

Video transcript

Hi, everyone. Let's take a look at this practice. Problem together identify the immune cell that is directly stimulated by helper T cells, an adaptive antibody mediated immunity. The answer options are a cytotoxic T cells. BB cells, c macrophages and d natural killer cells. Well, what is adaptive antibody mediated immunity to answer that? Let's break down the name. So adaptive refers to the fact that this type of immunity is specific. It builds up over time in response to specific antigens. Antibody mediated means that it relies on antibody production. So it's immunity to specific antigens and results in antibody production. Now, in order to produce those antibodies, helper T cells stimulate or activate a specific cell type. What is that cell option? A cytotoxic T cells, these cells directly attack specific antigens and kill cells that have those antigens since they attack specifically and directly to those antigens. They are part of adaptive cell mediated immunity. They do not rely on antibodies. So option A is incorrect. Option. C macrophages, macrophages are stimulated by the helper T cells. However, it is part of innate immunity, not the adaptive antibody mediated immunity. So option C is incorrect. Option D natural killer cells. They are part of innate immunity as well and they identify and destroy abnormal cells in the body. They are not stimulated by helper T cells. So, option D is incorrect. The correct answer is B cells. When they are stimulated by helper T cells, they divide and produce memory B cells and plasma cells that will secrete antibodies. So the correct answer is option BB cells. All right, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.