All right, guys, this is gonna be a quick video on Theo's towels and Raney Nickel reduction. So, guys, we're not going to spend a whole lot of time on this topic because it turns out that a thigh was a towel is really the same exact thing as an ass hotel. Except that instead of using an alcohol, you're using a file, right? So a Thile would just be a group. That r S H, which is really the same thing, is our Ohh. Remember, that s is right below Oh, on the periodic table. So it even reacts. Very, very similar Has those two lone pairs and everything. Okay, so in this case, you could see that I have my carbon eel on. I'm reacting it with what's actually called a die file here. Now, you don't always have to react with the dai file, but if you want to get a cyclic, If I was to tell, then you need to use a die file. If you want to get in a cyclic one, then you would use to equivalents of just a regular file. Okay, Now, the biggest difference being that between this direction that settles is that we do use a specific acid instead of how for a settles I told you is it doesn't really matter. It could be any proton donating acid for Theo's hotels. Typically, we use BF three, which, if you guys remember, is actually a strong Lewis acid. Okay, the biggest difference between this mechanism and the bronze said Lowry mechanism for, um as the towels is gonna be that in your first step instead of protein ating the, uh oh, the oh, actually just starts to donate its electrons to the empty orbital, which again makes a resident structure with a positive charge down here. Okay, So other than that, the mechanisms really pretty much identical. It's just that you're using a Lewis acid instead of a bronze, said Laurie Acid in this case. Okay, so now we get to the thigh hospital, which is this? And guys Theo, as the towels are also important protecting groups in organic chemistry. So you could use a that was a tell as a protecting group, and then that would be it. You just stop there and then you go back when you wanna. When you want to regenerate the carbon deal But there's a very important secondary reaction that Onley Theo hospitals can undergo that we wanna make sure that we learn here. That secondary reaction is when you combine a psych hospital with Raney Nickel Raney Nickel is a strong reducing agent. Okay, I'm gonna put here strong reducing agent troops reduce that works specifically with Theo's tells. And what it does is it replaces the entire, um, sulfur ring or the die thigh os tra ring with h is okay, So the Raney nickel catalyst is a great way to remove carbon meals altogether. So if your intention from the beginning was just let me get rid of that carbon eel and make it into an Al cane, then thigh was a towel with Raney. Nickel is the way to go. Okay, So, guys, we don't let you guys do this example here. Um, notice that there's multiple steps. First, I'm actually starting off within a settle. Then I'm reacting with dilute acid, so you can try to think what's going to go on there, so draw the structures for a be and see, and then we'll be done with this topic. So go ahead and do that, and then I'll do it for you.
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Raney Nickel Reduction
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Alright. So product A is just gonna be the reversed reaction of my ass. It'll leading to the original carbon Neil, because dilute, pass it, as we know, is going to be able to carry out the reverse reaction. So how do we know what that carbon you will look like? Well, it's actually not that hard. What I would do is I would split this down the middle and I would say anything past the those were actually I'll put it on the O's. Anything past the O's must have come from the alcohol and anything on this side must have come from the carbon eel. Okay, So what that means is that my alcohol originally looked like this. As you can see, those to the two carbons that were in between the those are still there. And that must have reacted within our group that looked like this. The only part of missing is the carbon eel. The carbonell goes where the ass it'll now is. So it would be cyclo beauty known. Okay, now I'm going to react that molecule with a thigh. I want to tell reaction and guys, what we're working with now is the key tone because the alcohol I don't care about that can leave. What I care about is the actual carbon meal. So now the carbon deal is going to react with tooth aisles and some kind of acid Doesn't tell me which one, but I don't really need to know what catalytic. Anyway, what this is going to do is it's gonna give me structure B, which is gonna be an asset or a thigh OAS to tell what I could do to get the structure as I could just draw the general structure and plug in the art groups. That's what I always do. So I would do something like this. S r s r carbon carbon. Okay. And now I'm just gonna change, Swap out the ours for what? The r was in my file. So my file is gonna be, I guess of propane file three carbons. So I would do and 123 And now I've got my assets. My thigh laws to tell. Cool. So that structure beat. We have a we have be. Now, what's Raney nickel gonna do to this? Oops. Whoa, whoa. Just second. I made a mistake. and that's okay. We can make mistakes. Except forgot. One part. The general structure for the Iowa Satele is Are are at the bottom. I also to substitute what those ours are. So what are those ours in particular? Are those Are this in like a pirate? It's the whole cycle. Butin on. So just replaced thes ours at the bottom with the square. Okay, now, that's correct. Now, when I use Raney Nickel Raney nickel is a great way to remove carbon nails completely. So I'm just gonna end up with cycle butane. Okay. Plus, I'm going to get whatever reacted. The Raney nickel and the assets the files tells. But I don't care about that. At this point. I just care about the organic product, which is gonna be the cyclo butane. Okay, awesome guys. So just a nice little review of thought. It was a towels and Raney nickel. Let's move onto the next topic.