Blocking Groups - Sulfonic Acid
19. Reactions of Aromatics: EAS and Beyond / Blocking Groups - Sulfonic Acid / Problem 1
Unlike other electrophilic aromatic substitutions, benzene sulfonation is reversible. Sulfonic acid can be added to the benzene ring and removed later. This makes the sulfonic acid group alternatively known as the "blocking group." Show how to synthesize 1,2,3-tribromobenzene starting from benzene, using sulfonation and de-sulfonation as intermediate steps.
Was this helpful?
Learn this concept