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20. Carboxylic Acid Derivatives:NAS - Part 3 of 3

22. Carboxylic Acid Derivatives: NAS / Lactones, Lactams and Cyclization Reactions / Problem 7

Show how to achieve each of the synthetic transformations shown below.

A

Transformation of a cyclic amine to a lactone using heat and NaBH4.

B

Cyclic amine reacting with a chlorinated lactone, followed by reduction.

C

Cyclic amine reacting with a chlorinated lactone, followed by DCC and LiAlH4.

D

Cyclic amine reacting with a lactone in HCl, followed by reduction steps.

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