Organic Chemistry
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Aminoglycosides are relatively stable in basic conditions, but it is readily cleaved by acid. Draw a mechanism for acid-catalyzed hydrolysis of an aliphatic aminoglycoside.
Ribonucleosides require a relatively strong acid to be hydrolyzed. Why are uridine and guanosine not easily hydrolyzed? Why is their stability crucial for the survival of living organisms?
Consider the following reaction of β-D-galactose with isopropylamine and explain why only a small amount of acid is used for the formation of an N-glycoside.