10. Addition Reactions
Carbene
Problem 16.22
Textbook Question
Textbook QuestionTo determine the stereochemistry of curacin A by synthesis, it would have been necessary to prepare all stereoisomers of the C₁₇―C₂₀ cyclopropane fragment. How would the reaction in Figure 16.30 be modified to produce the other stereoisomers shown here? [Think about the concepts of stereoselectivity (Chapter 6) and stereospecificity (Chapter 8).]
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