22. Carboxylic Acid Derivatives: NAS
Decarboxylation Mechanism
2:16 minutes
Problem 18.69
Textbook Question
Textbook Question(••••) LOOKING AHEAD While acidic conditions were used in Assessment 18.68, decarboxylation of esters can also be conducted under basic conditions to give, at least temporarily, the enolate product shown. [We’ll learn more about the chemistry of enolates in Chapter 20.] Suggest a mechanism of this reaction. [Hint: The formation of chloromethane proceeds by an SN2 reaction.]
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