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Ch. 3 - Cell Structure and Function
Chapter 3, Problem 3.6a

Which of the following is true of Svedbergs?


a. They are not exact but are useful for comparisons.
b. They are abbreviated “sv.”
c. They are prokaryotic in nature but exhibit some eukaryotic characteristics.
d. They are an expression of sedimentation rate during high-speed centrifugation.

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1
Understand that Svedbergs (S) are units used to describe the sedimentation rate of particles during centrifugation.
Recognize that sedimentation rate is influenced by the size, shape, and density of the particles, as well as the density and viscosity of the medium.
Note that Svedbergs are not exact measurements but are useful for comparing the sedimentation rates of different particles.
Remember that Svedbergs are not abbreviated as 'sv.'; the correct abbreviation is 'S'.
Identify that Svedbergs are not related to prokaryotic or eukaryotic characteristics but are purely a measure of sedimentation rate.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Svedberg Unit

The Svedberg unit (abbreviated as 'sv') is a measure of the sedimentation rate of particles in a centrifuge, reflecting their size, shape, and density. It is not a direct measure of mass but rather indicates how quickly a particle sediments under centrifugal force. This unit is particularly useful in biochemistry and molecular biology for characterizing ribosomes and other macromolecules.
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Sedimentation Rate

Sedimentation rate refers to the speed at which particles settle out of a solution when subjected to centrifugal force. This rate is influenced by factors such as the particle's size, shape, and density, as well as the viscosity of the medium. Understanding sedimentation is crucial for techniques like ultracentrifugation, which separates cellular components based on their physical properties.
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Centrifugation

Centrifugation is a laboratory technique that uses rapid spinning to create a force that separates components of a mixture based on their density. During high-speed centrifugation, particles are subjected to forces much greater than gravity, allowing for the isolation of cellular organelles, proteins, and nucleic acids. The effectiveness of this process is often quantified using Svedberg units.
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