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Ch.22 Carbohydrate Metabolism
Chapter 22, Problem 2242

Which cells, liver, muscle, or brain, use the following pathways?


a. Glycolysis

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1
Understand the process of glycolysis: Glycolysis is the metabolic pathway that converts glucose into pyruvate, releasing energy and forming ATP.
Identify the primary cells that utilize glycolysis: Glycolysis occurs in almost all cells, but it is especially important in cells that require quick energy.
Consider the liver: The liver uses glycolysis, but it is more involved in gluconeogenesis and glycogen storage.
Consider muscle cells: Muscle cells heavily rely on glycolysis for rapid energy production, especially during intense exercise when oxygen is limited.
Consider brain cells: The brain relies on glycolysis as it requires a constant supply of glucose for energy, even though it primarily uses oxidative phosphorylation for ATP production.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Glycolysis

Glycolysis is a metabolic pathway that converts glucose into pyruvate, producing a small amount of ATP and NADH in the process. It occurs in the cytoplasm of cells and is the first step in both aerobic and anaerobic respiration. This pathway is crucial for energy production, especially in cells that require quick energy, such as muscle cells during intense exercise.
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Cellular Metabolism

Cellular metabolism encompasses all biochemical reactions that occur within cells, including catabolic and anabolic pathways. It is essential for maintaining cellular functions, energy production, and the synthesis of necessary biomolecules. Different cell types, such as liver, muscle, and brain cells, have distinct metabolic profiles that dictate their energy needs and substrate utilization.
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Tissue-Specific Metabolism

Tissue-specific metabolism refers to the unique metabolic pathways and preferences exhibited by different types of cells. For instance, liver cells are adept at gluconeogenesis and glycogen storage, while muscle cells primarily rely on glycolysis and oxidative phosphorylation for energy during physical activity. Understanding these differences is vital for comprehending how various tissues utilize metabolic pathways like glycolysis.
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Specific Gravity