Name the following pathways:


c. Pathway for synthesis of glucose from lactate

Verified step by step guidance

1. Identify the process: The synthesis of glucose from lactate is a metabolic pathway.
2. Recognize the pathway: This process is known as gluconeogenesis.
3. Understand the context: Gluconeogenesis is the formation of glucose from non-carbohydrate precursors, such as lactate, amino acids, and glycerol.
4. Note the location: This pathway primarily occurs in the liver and, to a lesser extent, in the kidney.
5. Connect to broader metabolism: Gluconeogenesis is crucial for maintaining blood glucose levels during fasting or intense exercise.

Key Concepts

Gluconeogenesis

Gluconeogenesis is the metabolic pathway through which organisms synthesize glucose from non-carbohydrate precursors, such as lactate, glycerol, and certain amino acids. This process primarily occurs in the liver and, to a lesser extent, in the kidneys. It is crucial for maintaining blood glucose levels during fasting or intense exercise when glucose reserves are low.

Lactate

Lactate is a byproduct of anaerobic metabolism, particularly during intense exercise when oxygen levels are insufficient for aerobic respiration. It can be converted back into glucose through gluconeogenesis, allowing the body to recycle energy and maintain glucose homeostasis. This conversion is especially important in the Cori cycle, where lactate produced in muscles is transported to the liver for glucose synthesis.

Cori Cycle

The Cori cycle is a metabolic pathway that describes the conversion of lactate produced in muscles during anaerobic respiration back into glucose in the liver. This cycle helps to clear lactate from the bloodstream and provides a continuous supply of glucose for energy, especially during prolonged exercise. It illustrates the interconnectedness of muscle and liver metabolism in maintaining energy balance.