Glucose 6-phosphate is in a pivotal position in metabolism. Depending on conditions, glucose 6-phosphate follows one of several pathways. Under what conditions do the following occur?

d. Glycogenesis

Question

Glucose 6-phosphate is in a pivotal position in metabolism. Depending on conditions, glucose 6-phosphate follows one of several pathways. Under what conditions do the following occur?

d. Glycogenesis

Accepted Answer

All right. Hello everyone. So this question says that fructose six phosphate is a key metabolite in cellular processes. It can be directed towards different pathways based on certain conditions. Under what circumstances does glycolysis take place? Now, before we talk about the specific entry choices here of which there are four labeled A through D. Let's just talk briefly about the role of glycolysis in metabolism. So like the name implies glycolysis is the breakdown oops of sugar. It's the breakdown of sugar that mainly includes glucose, but other monosaccharide can be converted into glycolytic intermediates. So when is the breakdown of sugar necessary when it comes to metabolism as a whole? Well, in this particular case, the breakdown of sugar is going to be encouraged in situations where the level of blood glucose rises, right? Because if you have more sugar in the body, that's a sign that your metabolism should go ahead and break down that sugar to produce energy to produce ATP specifically and insulin, if you recall is the hormone that is activated in response to higher glucose levels in the blood. So with that in mind, let's go ahead and talk about these answer choices starting off with option A option A says when there's an energy deficit, low blood glucose levels and Glucagon release. So based on our discussion earlier about the role of glycolysis, we can see how option A is going to be incorrect because here glycolysis is going to be activated, it's going to be necessary when there's a need to harvest energy from glucose that has been consumed, right? That has been ingested. Now, lo low blood glucose levels and Glucagon release are linked to each other because Glucagon is going to oppose the function of insulin. Glucagon is active in conditions where the level of blood sugar is low. And so Glucagon is going to encourage or rather increase the rate of gluco neogenesis. It is released under conditions of low blood sugar to go ahead and create new glucose molecules and compensate for that lower level. So option A is incorrect, rather low low blood sugar is not going to encourage the breakdown of sugar, it's going to encourage instead the synthesis of sugar. And from here, we move on to option B which says during periods of fasting, high blood glucose levels and insulin release. So option B is one that we can eliminate for multiple reasons. First of all, fasting implies that you are not eating anything at a certain time. Fasting is associated with low blood glucose levels. And when you have blood low blood glucose levels, as we talked about before, in option A glucagon is going to be released instead to promote leuko genesis that tries to compensate for that lower blood sugar. So option B is incorrect. Now, option C on the other hand says after a carbohydrate rich meal, high blood glucose levels and insulin release, this is correct. This is correct because when talking about the background of glycolysis, we specifically mention that glycolysis is active in conditions where the level of blood glucose rises. An example of conditions where blood glucose rises is after eating a meal that's rich in carbohydrates. Carbohydrates introduce sugar, specifically glucose that must be broken down, right. So that's why insulin is released and glycolysis is promoted to break down that excess sugar. So C is correct, but just for the sake of completion, let's talk about option D, option D says in response to stress low blood glucose levels and adrenaline release. All right. So here it's worth remembering the fact that during conditions of stress and lower blood glucose levels, gluconeogenesis and glycogenolysis are favored instead because the goal under these conditions is to increase blood glucose levels. Now, adrenaline otherwise known as epinephrine is going to stimulate gluconeogenesis and glycogenolysis, as opposed to glycolysis. Rather, you don't want to break down sugar in these circumstances, you want to produce more of it. So D as in correct and just to reiterate our answer is option C and so with that being said, thank you so very much for watching and I hope you found this helpful.

Glucose 6-phosphate is in a pivotal position in metabolism. Depending on conditions, glucose 6-phosphate follows one of several pathways. Under what conditions do the following occur?

d. Glycogenesis

Verified Solution

Key Concepts

Glycogenesis

Insulin Regulation

Metabolic Pathways

Glucose 6-phosphate is in a pivotal position in metabolism. Depending on conditions, glucose 6-phosphate follows one of several pathways. Under what conditions do the following occur?d. Glycogenesis

Verified Solution

Key Concepts

Glycogenesis

Insulin Regulation

Metabolic Pathways

Glucose 6-phosphate is in a pivotal position in metabolism. Depending on conditions, glucose 6-phosphate follows one of several pathways. Under what conditions do the following occur?

d. Glycogenesis