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Ch.21 The Generation of Biochemical Energy
Chapter 21, Problem 19.18

Which vitamin provides us with each of the following?


b. Coenzyme A

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1
Identify the role of Coenzyme A in the body. Coenzyme A is essential for the synthesis and oxidation of fatty acids and the oxidation of pyruvate in the citric acid cycle.
Understand that Coenzyme A is derived from a vitamin. Specifically, it is synthesized from pantothenic acid, which is a B vitamin.
Recognize that pantothenic acid is also known as Vitamin B5.
Recall that Vitamin B5 is water-soluble and is found in a variety of foods, including meats, vegetables, and whole grains.
Conclude that the vitamin responsible for providing Coenzyme A is Vitamin B5, also known as pantothenic acid.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Vitamin B5 (Pantothenic Acid)

Vitamin B5, also known as pantothenic acid, is essential for synthesizing coenzyme A (CoA). CoA plays a critical role in fatty acid metabolism and the synthesis of neurotransmitters. It is involved in the Krebs cycle, which is vital for energy production in cells. A deficiency in vitamin B5 can lead to various metabolic issues.
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Coenzyme A (CoA)

Coenzyme A is a crucial cofactor in biochemical reactions, particularly in the metabolism of fatty acids and carbohydrates. It facilitates the transfer of acyl groups, which are important for energy production and the synthesis of biomolecules. CoA is synthesized from vitamin B5, highlighting the interdependence of vitamins and metabolic processes.
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Vitamin Deficiency and Metabolism

Vitamin deficiencies can significantly impact metabolic pathways, leading to various health issues. For instance, a lack of vitamin B5 can impair the synthesis of CoA, disrupting energy metabolism and fatty acid synthesis. Understanding the role of vitamins in metabolism is crucial for maintaining overall health and preventing deficiency-related diseases.
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Metabolic Pathways Concept 2