What type of enzyme regulation occurs in the following situations?

a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.

Question

What type of enzyme regulation occurs in the following situations?

a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.

Accepted Answer

All right. Hello everyone. So this question is asking us what type of enzyme regulation is being described in the following scenario. And the scenario is that the accumulation of A TP a product of cellular respiration inhibits the first enzyme in the process that breaks down glucose option. A says competitive inhibition. B says allosteric activation, C says feedback inhibition and D says noncompetitive inhibition. So before we focus more on the specific scenario, let's just clarify what these answer choices actually mean starting off with competitive inhibition. Now, competitive inhibition involves competition or the active site of an enzyme. So essentially the inhibitor is going to compete with the substrate of an enzyme for binding to the active side of the enzyme that reduces the activity of the enzyme because less of the substrate is able to bind to it. Now, on the other hand, we have allosteric activation that specifically describes a regulator binding to the allosteric site of an enzyme. Now, the allosteric site notably is not the active site. It is a separate location on the enzyme where regulators can bind to. After binding regulators have the power to change the structure of the active site thereby affecting its catalytic activity. Now, on the other hand, we have noncompetitive inhibition. Now, essentially noncompetitive inhibition is another way of describing allosteric inhibition. Because all that noncompetitive means to say is that the regulator binds to a location other than the active site. So options B and D essentially say the same thing or actually B is for activation D is for inhibition just to clarify. But noncompetitive is another way of describing allosteric in general. And so from here, let's go ahead and talk a little bit more about the reaction in question. So starting off here, we have glucose as our starting material acting in an enzyme. We'll call this E one for the sake of discussion. And E one produces ATP. Now, based on the scenario described the enzyme is sensitive to the concentration of A TP that's in the cell. So essentially, depending on the needs of the cell, right. If there's too much of ATP within the cell, the enzyme can be deactivated because A TP can act on the enzyme and alert the enzyme that there's no need to make more ATP. There is enough of it in the cell. So essentially at P, which is the product of the enzyme itself is going to give feedback to the enzyme. It's going to let the enzyme know that it can be deactivated because there is enough at TP for the moment. So that's feedback inhibition, which is why option C is going to be the correct answer. And so with that being said, thank you so very much for watching and I hope you found this helpful.

What type of enzyme regulation occurs in the following situations?

a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.

Verified Solution

Key Concepts

Feedback Inhibition

Enzyme Kinetics

Allosteric Regulation

What type of enzyme regulation occurs in the following situations?a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.

Verified Solution

Key Concepts

Feedback Inhibition

Enzyme Kinetics

Allosteric Regulation

What type of enzyme regulation occurs in the following situations?

a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.