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Ch.19 Enzymes and Vitamins
Chapter 19, Problem 19.29

Explain how the following mechanisms regulate enzyme activity.


b. Genetic control

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1
Genetic control of enzyme activity involves the regulation of enzyme synthesis at the level of gene expression.
The process begins with the transcription of DNA into mRNA, which is then translated into proteins, including enzymes.
Regulation can occur at the transcriptional level, where certain genes are turned on or off in response to cellular signals.
This regulation ensures that enzymes are produced only when needed, conserving energy and resources within the cell.
Factors such as transcription factors, enhancers, and repressors play crucial roles in the genetic control of enzyme activity.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Enzyme Regulation

Enzyme regulation refers to the various mechanisms that control the activity of enzymes, ensuring that metabolic processes occur at the right time and in the right amounts. This regulation can occur through several means, including allosteric regulation, covalent modification, and genetic control, which collectively help maintain homeostasis within the cell.
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Genetic Control

Genetic control of enzyme activity involves the regulation of gene expression that encodes enzymes. This means that the synthesis of enzymes can be increased or decreased based on the cell's needs, often in response to environmental changes or developmental signals, allowing for precise control over metabolic pathways.
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Transcription and Translation

Transcription and translation are the two key processes through which genetic information is converted into functional proteins, including enzymes. Transcription involves copying DNA into messenger RNA (mRNA), while translation is the process where ribosomes synthesize proteins based on the sequence of the mRNA, ultimately determining the levels and activity of enzymes in the cell.
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Transcription: mRNA Synthesis Concept 1