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Ch. 3 - Cell Division and Chromosome Heredity
Chapter 3, Problem 11

Describe the role of the following structures or proteins in cell division:

cohesin protein

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Cohesin is a protein complex that plays a crucial role in holding sister chromatids together after DNA replication.
During the S phase of the cell cycle, cohesin forms a ring-like structure around the sister chromatids, ensuring they remain attached.
This attachment is essential for proper chromosome alignment and segregation during mitosis and meiosis.
In the metaphase stage of cell division, cohesin helps align the sister chromatids at the metaphase plate.
At the onset of anaphase, cohesin is cleaved by the enzyme separase, allowing sister chromatids to separate and move to opposite poles of the cell.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Cohesin Protein

Cohesin is a protein complex that plays a crucial role in holding sister chromatids together during cell division. It forms a ring-like structure that encircles the chromatids, ensuring they remain attached until the appropriate stage of mitosis or meiosis. This attachment is vital for accurate chromosome segregation, preventing aneuploidy, which can lead to various genetic disorders.
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Cell Division

Cell division is the process by which a parent cell divides into two or more daughter cells. It encompasses two main types: mitosis, which results in two identical daughter cells for growth and repair, and meiosis, which produces gametes for sexual reproduction. Proper regulation of cell division is essential for maintaining genetic stability and organismal development.
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Chromatid Separation

Chromatid separation is a critical phase in cell division where sister chromatids are pulled apart to opposite poles of the cell. This process occurs during anaphase of mitosis and meiosis, facilitated by the action of spindle fibers. The timely and accurate separation of chromatids is essential to ensure that each daughter cell receives the correct number of chromosomes.
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