Give descriptions for the following terms: nucleosome core particle

Question

Accepted Answer

Hi everyone. Here's our next problem which of the following statements is incorrect. Regarding the nucleosome core particle choice A, it is a complex structure composed of DNA wrapped around an october of histone proteins. Choice B. It helps regulate gene expression by controlling access to DNA Choice C. It is a fundamental unit of DNA packaging in eukaryotic cells. For choice D it is a protein that is involved in DNA replication. So let's think about these answer choices. Recalling that we need the incorrect statement. So looking at choice A saying it's a complex structure made up of DNA wrapped around an omer of histone proteins. And this is correct. This is true and therefore not our answer choice. The nucleosome core particle is part is the bead of the bead on a string structure of chromatin. So it has an octo of histone proteins with that double strand of DNA wound around it. That will actually lead us to our correct answer because we know the core particle is the structure of DNA wrapped around of protein core. So choice D it is a protein involved in DNA replication is our correct answer because it's an incorrect statement. It gets a little confusing but it's a false statement because it's not a protein, it's this complex of DNA wound around and a protein omer. Just to be thorough. We'll look at our other answer. Choices. Choice B helps to regulate gene expression by controlling access to DNA. And this is another true statement because that DNA could be wound more tightly or more loosely around the October, which if it's wrapped very tightly, it's part of the uh very tightly packed chromatin, the heterochromatin. And that kind of chromatin is not many genes are transcribed from it because the whole transcription machinery physically can't access that tightly packed chromatin when it's more loosely wound genes can be transcribed from it. So it's actually as a result affects gene expression. So that's a true statement and therefore not our answer. Then when we look at choice C, it says it is a fundamental unit of DNA packaging in new Caro cells. And this is true. Also, there's so much DNA, it would take up a huge amount of space if it weren't very efficiently and tightly packed together. And it's done in this bead on a string structure of which the nucleosome core particle is that bead, as we said. So that's a true statement and therefore not our answer. So again, the incorrect statement about the nucleosome core particle is choice D it is a protein that is involved in DNA replication. See you in the next video.

Give descriptions for the following terms: nucleosome core particle

Verified Solution

Key Concepts

Nucleosome Structure

Histones

Chromatin Packaging