Ch. 11 - DNA Replication and Recombination
Chapter 11, Problem 4
Describe the role of ¹⁵N in the Meselson–Stahl experiment.
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Related Practice
Textbook Question
In this chapter, we focused on how DNA is organized at the chromosomal level. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions:
How do we know that satellite DNA consists of repetitive sequences and has been derived from regions of the centromere?
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Textbook Question
Write a short essay that distinguishes between the terms replication and synthesis, as applied to DNA. Which of the two is most closely allied with the field of biochemistry?
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Textbook Question
Compare conservative, semiconservative, and dispersive modes of DNA replication.
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Textbook Question
Predict the results of the experiment by Taylor, Woods, and Hughes if replication were (a) conservative and (b) dispersive.
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Textbook Question
What are the requirements for in vitro synthesis of DNA under the direction of DNA polymerase I?
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Textbook Question
In Kornberg's initial experiments, it was rumored that he grew E. coli in Anheuser-Busch beer vats. (Kornberg was working at Washington University in St. Louis.) Why do you think this might have been helpful to the experiment?
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