15. Genomes and Genomics
Genomics and Human Medicine
Problem 32
Textbook Question
Textbook QuestionThe CRISPR–Cas9 complex directs the Cas9 endonuclease to a specific genomic locus. If the endonuclease domain is inactivated and replaced with a transcriptional activator (or repressor) domain, what would be the functional consequence of directing such a complex to a specific chromosomal location?
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