Using the adenine–thymine base pair in this DNA sequence ...GCTC... ...CGAG... Give the sequence after a transversion mutation.

Key Concepts

Transversion Mutation

A transversion mutation is a type of point mutation where a purine base (adenine or guanine) is replaced by a pyrimidine base (cytosine or thymine), or vice versa. This contrasts with transitions, where a purine is replaced by another purine or a pyrimidine by another pyrimidine. Transversions can lead to significant changes in the protein sequence, potentially altering the function of the resulting protein.

DNA Base Pairing

DNA base pairing refers to the specific pairing of nitrogenous bases in the DNA double helix, where adenine pairs with thymine (A-T) and guanine pairs with cytosine (G-C). This complementary base pairing is crucial for DNA replication and transcription, ensuring that genetic information is accurately copied and expressed. Understanding base pairing is essential for predicting the effects of mutations on DNA sequences.

Effects of Mutations

Mutations can have various effects on an organism, ranging from benign to harmful. They can alter the amino acid sequence of proteins, potentially affecting their structure and function. Some mutations may lead to diseases or disorders, while others can provide beneficial traits that enhance survival. Analyzing the specific type of mutation, such as a transversion, helps in understanding its potential impact on gene expression and phenotype.