The eyes of Drosophila develop from imaginal discs, grou...

Question

The eyes of Drosophila develop from imaginal discs, groups of cells set aside in the fly embryo that differentiate into the adult structures during the pupal stage. Despite their importance in nature, eyes are dispensable for fruit-fly life in the laboratory.

Devise a genetic screen to identify genes directing development of the fly eye.

Accepted Answer

Hi, everybody. Let's look at our next problem. One of the most significant advantages of using random muto genesis in genetic screens is choice A, it generates a large population of organisms with identical mutations. Choice B, it generates a large population of organisms with diverse mutations. Choice C, it introduces specific mutations in genes of interest and choice D. It eliminates mutations from genes of interest. Well, as we look at our answer, choices, we can just eliminate choice D right away. Choice D says it eliminates mutations. But we're talking about muto genesis literally causing mutations and we can eliminate choice C. It introduces specific mutations because we're talking about random muto genesis, the intro introduction of random changes to the DNA. So now we're just looking at whether it generates a population with identical mutations or diverse mutations. And it is choice B a large population with diverse mutations. Because in random muto genesis, you're just throwing mutagens at your DNA to cause a bunch of different changes in different places. So that will generate different mutations. So we can cross out choice a identical mutations. You would only say identical mutations if you were using a specific, targeted way to change the DNA. And why would you do that? Well, if you're trying to look at the connection between genotype and phenotype, you'd want to see a lot of different possible phenotypes and their genotypes to really explore that connection solely. If you just look at one single mutation, you're not going to see uh the realm of possibilities that are there. So again, our answer here will be choice b large population with diverse mutations. See you in the next video.

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