Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Epistasis and Complementation
Problem 23f
Textbook Question
Three strains of green-seeded lentil plants appear to have the same phenotype. The strains are designated G₁, G₂, and G₃. Each green-seeded strain is crossed to a pure-breeding yellow-seeded strain designated Y. The F₁ of each cross are yellow; however, self-fertilization of F₁ plants produces F₂ with different proportions of yellow- and green-seeded plants as shown below.
![Table showing F1 and F2 phenotypes of green-seeded lentil strains G1, G2, G3 crossed with yellow strain Y.](https://lightcat-files.s3.amazonaws.com/problem_images/8e34b6e48ad09aa1-1678813057143.jpg)
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1
Identify the phenotypic ratio in the F2 generation for each cross: G1 x Y (1:3), G2 x Y (7:9), G3 x Y (37:27).
Recall that a 3:1 ratio in the F2 generation suggests a single gene with two alleles, where one allele is dominant.
For the G1 x Y cross, the 1:3 ratio indicates segregation of alleles at one gene locus.
For the G2 x Y cross, the 7:9 ratio suggests a more complex inheritance pattern, possibly involving two genes with epistatic interactions.
For the G3 x Y cross, the 37:27 ratio indicates an even more complex pattern, potentially involving multiple genes with interactions.
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