Look over the 10 diseases approved for genetic health ri...

Question

Look over the 10 diseases approved for genetic health risk assessment listed in Application Chapter B. Select one disease other than the three discussed in Application Chapter B or in this chapter (alpha-1 antitrypsin deficiency, late-onset Alzheimer disease, and celiac disease) or another of the diseases of your choice. Do a brief Internet search to find and download (1) one article for a nonscientific audience identifying the gene or genes whose alleles are associated with occurrence of the disease and (2) one scientific paper that provides data supporting the association of specific alleles of the gene or genes with the disease. Write a short summary combining the information contained in the two papers.

Accepted Answer

Hi, everyone. Welcome back. Let's look at our next question. Which of the following statements about mutation is true. Choice. A mutations that occur in somatic cells are heritable b mutations that occur in germ cells are non heritable choice. C, somatic mutations are not transmitted to the next generation or choice. D germline mutations are not transmitted to the next generation. So we can see this is a pretty straightforward question just looking to distinguish between somatic cells and germline cells and in which ones do mutations pass on to the next generation or get inherited. Well, hopefully we recall that the germline cells are those haploid games that combine during fertilization. So they are the cells whose genotype will get passed to the next generation. Whereas the somatic cells are those diploid cells that are not reproductive cells. So any mutations that occur to the somatic cells will not get passed on to the next generation. It's only the gametes whose chromosomes come together in fertilization and get passed on. So we know that germline cells are the ones whose mutations will be passed on. So with that in mind, let's just sort through our answers here. So Choice A says that mutations that occur in somatic cells are heritable. So that is not true. So we'll cross that out. And Choice B it says if they're in the mutations are in germ cells, they're non heritable. But that's not correct. A mutation in a germ cell is heritable. And choice C says that somatic mutations are not transmitted to the next generation and this is correct. So this is going to be our answer. But we'll just look quickly at choice C saying that germline mutations are not transmitted to the next generation. And of course, that is not true. So pretty straightforward question here. Our answer is choice C our true statement. Somatic mutations are not transmitted to the next generation. See you in the next video.

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