Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
1. Introduction to Genetics
Fundamentals of Genetics
2:02 minutes
Problem 10a
Textbook Question
Textbook QuestionDefine each of the following terms:
mutation
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mutation
A mutation is a change in the DNA sequence of an organism's genome. This alteration can occur due to various factors, including errors during DNA replication, exposure to radiation, or chemical agents. Mutations can be classified as point mutations, which involve a single nucleotide change, or larger-scale mutations that affect larger segments of DNA. They can lead to changes in protein function and may have neutral, beneficial, or harmful effects on the organism.
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10:48
Mutations and Phenotypes
Types of Mutations
Mutations can be categorized into several types, including silent, missense, and nonsense mutations. Silent mutations do not change the amino acid sequence of a protein, while missense mutations result in a different amino acid being incorporated, potentially altering protein function. Nonsense mutations create a premature stop codon, leading to truncated proteins. Understanding these types is crucial for predicting the potential impact of mutations on an organism's phenotype.
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10:48
Mutations and Phenotypes
Mutagenesis
Mutagenesis refers to the process by which mutations are induced in an organism's DNA. This can occur naturally through environmental factors or be induced artificially in laboratory settings using mutagens, such as chemicals or radiation. Studying mutagenesis is important for understanding the mechanisms of evolution, the development of genetic diseases, and the effects of environmental factors on genetic stability. It also plays a significant role in fields like biotechnology and medicine.
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04:29
Induced Mutations
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