Presented here are hypothetical findings from studies of heteroka...

Question

Presented here are hypothetical findings from studies of heterokaryons formed from seven human xeroderma pigmentosum cell strains:

XP1 XP2 XP3 XP4 XP5 XP6 XP7
XP1 -
XP2 - -
XP3 - - -
XP4 + + + -
XP5 + + + + -
XP6 + + + + - -
XP7 + + + + - - -
Note: + = complementation; - = no complementation

These data are measurements of the occurrence or nonoccurrence of unscheduled DNA synthesis in the fused heterokaryon. None of the strains alone shows any unscheduled DNA synthesis. Which strains fall into the same complementation groups? How many different groups are revealed based on these data? What can we conclude about the genetic basis of XP from these data?

Accepted Answer

Hey everyone, Let's take a look at this question together. What is the inheritance pattern of zero derma pigmentosa. So let's recall what we know about the disorder? Zero derma pigmentosa. To figure out which of the following best represents its inheritance pattern. So we know that zero derma pigmentosa is a genetic disorder that free disposes individuals too severe skin abnormalities as well as cancers and other symptoms, including developmental and neurological defects. And so the fact that it predisposes these individuals means that the gene for zero derma pigmentosa um is not dominant and that it is recessive and it is auto zonal recessive or answer Choice B. The correct answer because their dharma pigment tells them predisposes these individuals, meaning that they might not express the condition, however they do have that recessive gene for it. So there is that possibility that they could express the disorder depending on their genotype. So answer choice B. Best represents the inheritance pattern of zero derma pigment, awesome because it is an autism, a recessive genetic disorder. I hope you found this video to be helpful. Thank you and goodbye.

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