8. DNA Replication
Overview of DNA Replication
1:25 minutes
Problem 27a
Textbook Question
Textbook QuestionDNA polymerases in all organisms add only 5' nucleotides to the 3' end of a growing DNA strand, never to the 5' end. One possible reason for this is the fact that most DNA polymerases have a proofreading function that would not be energetically possible if DNA synthesis occurred in the 3' to 5' direction. Consider the information in your sketch and speculate as to why proofreading would be problematic.
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