20. Quantitative Genetics
QTL Mapping
3:17 minutes
Problem 29e
Textbook Question
Textbook QuestionIn 1988, Horst Wilkens investigated blind cavefish, comparing them with members of a sibling species with normal vision that are found in a lake [Wilkens, H. (1988). Evol. Biol. 25:271–367]. We will call them cavefish and lakefish. Wilkens found that cavefish eyes are about seven times smaller than lakefish eyes. F₁ hybrids have eyes of intermediate size. These data, as well as the F₁×F₁ cross and those from backcrosses (F₁×cavefish and F₁×lakefish), are depicted below. Examine Wilkens's results and respond to the following questions:
Based strictly on the F₁ and F₂ results of Wilkens's initial crosses, what possible explanation concerning the inheritance of eye size seems most feasible?
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