In humans, SRY is located near a pseudoautosomal region (PAR) of the Y chromosome, a region of homology between the X and Y chromosomes that allows them to synapse during meiosis in males and is a region of crossover between the chromosomes. The diagram below shows SRY in relation to the pseudoautosomal region.

About 1 in every 25,000 newborn infants is born with sex reversal; the infant is either an apparent male but with two X chromosomes or an apparent female but with an X and a Y chromosome. Explain the origin of sex reversal in human males and females involving the SRY gene. (Hint: See Experimental Insight 3.1 for a clue about the mutational mechanism.) 

Verified step by step guidance

1. Understand that the SRY gene is crucial for male sex determination and is located near the pseudoautosomal region (PAR) on the Y chromosome.
2. Recognize that during meiosis, the X and Y chromosomes can undergo crossover in the PAR region, which is a region of homology between them.
3. Consider that an abnormal crossover event can occur where the SRY gene is transferred from the Y chromosome to the X chromosome.
4. Realize that if the SRY gene is present on an X chromosome, an individual with two X chromosomes (XX) can develop male characteristics, leading to sex reversal.
5. Similarly, if the Y chromosome loses the SRY gene due to such a crossover, an individual with an X and a Y chromosome (XY) can develop female characteristics, also resulting in sex reversal.