- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Translation
Problem 40a
Textbook Question
For each of the following tRNA anticodon sequences, give the sequence of the corresponding codon sequence, the amino acid carried by the tRNA, and the corresponding DNA coding strand sequence and polarity.
3′-AUG-5′

1
Identify the tRNA anticodon sequence: 3′-AUG-5′.
Determine the corresponding mRNA codon by pairing the anticodon with complementary bases: 5′-UAC-3′.
Use the genetic code to find the amino acid corresponding to the mRNA codon 5′-UAC-3′, which is Tyrosine (Tyr).
Identify the DNA coding strand sequence by replacing uracil (U) in the mRNA with thymine (T) and maintaining the same polarity: 5′-TAC-3′.
Ensure the polarity of the DNA coding strand is 5′ to 3′, matching the mRNA codon sequence polarity.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
tRNA and Anticodons
Transfer RNA (tRNA) molecules are essential for translating mRNA sequences into proteins. Each tRNA has an anticodon that is complementary to a specific codon on the mRNA. The anticodon allows the tRNA to recognize and bind to the corresponding codon, ensuring the correct amino acid is added to the growing polypeptide chain during protein synthesis.
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Codons and Amino Acids
Codons are sequences of three nucleotides in mRNA that specify a particular amino acid during translation. Each codon corresponds to one of the 20 standard amino acids, as defined by the genetic code. For example, the codon AUG not only codes for the amino acid methionine but also serves as the start signal for protein synthesis.
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DNA Coding Strand and Polarity
The DNA coding strand is the strand of DNA that has the same sequence as the mRNA (except for thymine in DNA being replaced by uracil in RNA). It runs in a 5' to 3' direction, which is crucial for transcription and translation processes. Understanding the polarity of nucleic acids is vital, as it influences how genetic information is read and translated into proteins.
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The Genetic Code
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