Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Trihybrid Cross
1:12 minutes
Problem 22b
Textbook Question
Textbook QuestionAn organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table. 20 AaBbCc 20 AaBbcc 20 aabbCc 20 aabbcc 5 AabbCc 5 Aabbcc 5 aaBbCc 5 aaBbcc Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Testcross
A testcross is a genetic cross between an individual with an unknown genotype and a homozygous recessive individual. This method helps determine the genotype of the unknown individual based on the phenotypes of the offspring. In this case, the organism with genotype AaBbCc is crossed with aabbcc, allowing the observation of the segregation of alleles in the progeny.
Linkage and Crossover
Linkage refers to the tendency of genes located close together on the same chromosome to be inherited together. Crossover is a process during meiosis where homologous chromosomes exchange genetic material, leading to new allele combinations. In this scenario, the assumption of no crossover means that the alleles for the three genes are inherited together without recombination, affecting the expected progeny ratios.
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Genotypic Ratios
Genotypic ratios represent the relative frequencies of different genotypes produced in a genetic cross. In this case, the progeny genotypes from the testcross can be analyzed to determine the ratios of dominant and recessive traits. Understanding these ratios is crucial for predicting the inheritance patterns and assessing the effects of linkage on the offspring's genetic makeup.
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