Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
17. Mutation, Repair, and Recombination
Types of Mutations
Problem 28c
Textbook Question
Textbook QuestionMost organisms display a circadian rhythm, a cycling of biological processes that is roughly synchronized with day length (e.g., jet lag occurs in humans when rapid movement between time zones causes established circadian rhythms to be out of synch with daylight hours). In Drosophila, pupae eclose (emerge as adults after metamorphosis) at dawn.
In most plants, such as Arabidopsis, genes whose encoded products have roles related to photosynthesis have expression patterns that vary in a circadian manner. Using this knowledge, how would you screen for Arabidopsis mutants that have an impaired circadian rhythm?
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Circadian Rhythm
Circadian rhythms are internal biological processes that follow a roughly 24-hour cycle, influencing various physiological functions such as sleep-wake cycles, hormone release, and metabolism. These rhythms are regulated by an internal clock and can be affected by external cues like light and temperature. Understanding circadian rhythms is crucial for studying how organisms adapt their biological functions to the day-night cycle.
Genetic Screening
Genetic screening is a method used to identify and isolate mutants with specific phenotypic traits, such as impaired circadian rhythms. In plants like Arabidopsis, researchers can use techniques such as mutagenesis followed by phenotypic analysis to find mutants that exhibit altered timing in gene expression related to circadian rhythms. This process helps in understanding the genetic basis of circadian regulation.
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Gene Expression Patterns
Gene expression patterns refer to the timing and level at which specific genes are activated or repressed in response to environmental cues, such as light. In Arabidopsis, genes involved in photosynthesis show circadian regulation, meaning their expression varies throughout the day. Analyzing these patterns is essential for identifying mutants with disrupted circadian rhythms, as changes in expression can indicate underlying genetic alterations.
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