- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Translation
Problem 40b
Textbook Question
For each of the following tRNA anticodon sequences, give the sequence of the corresponding codon sequence, the amino acid carried by the tRNA, and the corresponding DNA coding strand sequence and polarity.
3′-CCU-5′

1
Identify the tRNA anticodon sequence: 3′-CCU-5′.
Determine the corresponding mRNA codon by pairing the anticodon with complementary bases: 5′-GGA-3′.
Use the genetic code to find the amino acid specified by the mRNA codon 5′-GGA-3′. This codon codes for the amino acid Glycine (Gly).
Identify the DNA coding strand sequence that corresponds to the mRNA codon. The DNA coding strand is identical to the mRNA sequence, except that thymine (T) replaces uracil (U): 5′-GGA-3′.
Determine the polarity of the DNA coding strand: 5′-GGA-3′.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
tRNA and Anticodons
Transfer RNA (tRNA) molecules are essential for translating the genetic code into proteins. Each tRNA has an anticodon, a sequence of three nucleotides that pairs with a complementary codon on mRNA during translation. The specific anticodon 3′-CCU-5′ will pair with the corresponding mRNA codon, which is crucial for determining the amino acid that the tRNA carries.
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Codons and Amino Acids
Codons are sequences of three nucleotides in mRNA that specify a particular amino acid during protein synthesis. The genetic code is universal, meaning that each codon corresponds to a specific amino acid or a stop signal. For the anticodon 3′-CCU-5′, the corresponding mRNA codon is 5′-GGA-3′, which codes for the amino acid glycine.
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DNA Coding Strand and Polarity
The DNA coding strand is the strand of DNA that has the same sequence as the mRNA (except for thymine in DNA replacing uracil in RNA). The polarity of nucleic acid strands is important; DNA and RNA strands are read in the 5′ to 3′ direction. For the mRNA codon 5′-GGA-3′, the corresponding DNA coding strand sequence is 5′-CCT-3′, maintaining the correct polarity.
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