Go to the website http://www.cancer.gov and select 'Cancer Types'...

Question

Go to the website http://www.cancer.gov and select 'Cancer Types' on the top menu bar. Scroll down to 'Breast Cancer' and click. Select 'Cases & Prevention' from the options. Click 'More information' and select 'BRCA Mutations: Cancer Risk and Genetic Testing'. Use the information on this page to answer the following questions.

With regard to the results of genetic testing for BRCA1 and BRCA2 mutations, what is meant by a 'positive result'?

Accepted Answer

Hi, everyone. Let's look at our next question. A positive test result of BRC A one and BRC A two mutation testing indicates that the person has inherited a known harmful BRC A one or BRC A two variant, which of the following statements regarding the positive test result is true choice. A, it is certain that the person being tested will develop cancer. Choice B the tested individual might give the variant to their Children. Choice C, some people who inherit a harmful BRC A one or BRC A two variant never develop cancer or choice D both B and C. So we just need to think through what it means to have a positive test result for these mutations. And that means that the person has an increased risk of developing familial, early onset breast or ovarian cancer. When we look at our answer, choices, uh Choice A says it is certain that the person being tested will develop cancer. Well, this is not correct because it is not certain, it's an increased risk, but there are some people who will never go on to develop cancer despite having this harmful mutation in one or both genes. So with that in mind, then we know that choice C is correct. I'm not going to select it as the answer because again, we have that possibility that both B and C are correct. But I'm gonna put a little, I'm going to put a little dot Next to it to indicate it's a correct answer. Saying some people who inherit a harmful variant never develop cancer. So we just have to evaluate choice. B it says the tested individual might give the variant to their Children. Well, this is also correct if one has inherited a mutation, that mutation can be passed on to the next generation. So since both B and C are correct, our answer will be choice. D both B and C as the true statement regarding the positive test result for BRC A one and BRC A two mutation testing. See you in the next video.

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