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Ch.3 - Mass Relationships in Chemical Reactions
Chapter 3, Problem 81

Cisplatin [Pt(NH3)2Cl2], a compound used in cancer treat-ment, is prepared by reaction of ammonia with potassium tetrachloroplatinate: K2PtCl4 + 2 NH3 ----> 2 KCl + Pt(NH3)2Cl2 How many grams of cisplatin are formed from 55.8 g of K2PtCl4 and 35.6 g of NH3 if the reaction takes place in 95% yield based on the limiting reactant?

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Stoichiometry

Stoichiometry is the calculation of reactants and products in chemical reactions based on the balanced chemical equation. It involves using mole ratios derived from the coefficients of the balanced equation to determine how much of each substance is consumed or produced. In this case, stoichiometry will help identify the limiting reactant and calculate the theoretical yield of cisplatin.
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Limiting Reactant

The limiting reactant is the substance that is completely consumed first in a chemical reaction, thus determining the maximum amount of product that can be formed. To find the limiting reactant, one must compare the mole ratios of the reactants based on the balanced equation. In this scenario, identifying the limiting reactant is crucial for calculating the actual yield of cisplatin.
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Percent Yield

Percent yield is a measure of the efficiency of a chemical reaction, calculated as the ratio of the actual yield to the theoretical yield, multiplied by 100. It indicates how much product was obtained compared to what was expected based on stoichiometric calculations. In this problem, the 95% yield indicates that only 95% of the theoretical amount of cisplatin will be produced, which must be factored into the final calculation.
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Related Practice
Textbook Question

Limestone (CaCO3) reacts with hydrochloric acid according to the equation CaCO3 + 2 HCl ---> CaCl2 + H2O + CO2. If 1.00 mol of CO2 has a volume of 22.4 L under the reaction conditions, how many liters of gas can be formed by reaction of 2.35 g of CaCO3 with 2.35 g of HCl? Which reactant is limiting?

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Textbook Question
Sodium azide (NaN3) yields N2 gas when heated to 300 °C, a reaction used in automobile air bags. If 1.00 mol of N2 has a volume of 47.0 L under the reaction conditions, how many liters of gas can be formed by heating 38.5 g of NaN3? The reaction is
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Textbook Question
Acetic acid (CH3CO2H) reacts with isopentyl alcohol (C5H12O) to yield isopentyl acetate (C7H14O2), a fragrant substance with the odor of bananas. If the yield from the reaction of acetic acid with isopentyl alcohol is 45%, how many grams of isopentyl acetate are formed from 3.58 g of acetic acid and 4.75 g of isopentyl alcohol? The reaction is CH3CO2H + C5H12O ---> C7H14O2 + H2O
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Textbook Question
If 1.87 g of acetic acid (CH3COOH) reacts with 2.31 g of isopentyl alcohol (C5H12O) to give 2.96 g of isopentyl acetate (C7H14O2), what is the percent yield of the reaction?
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Textbook Question
If 3.42 g of K2PtCl4 and 1.61 g of NH3 give 2.08 g of cispla-tin (Problem 3.81), what is the percent yield of the reaction?
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Textbook Question

The reaction of tungsten hexachloride (WCl6) with bismuth gives hexatungsten dodecachloride (W6Cl12).

WCl6 + Bi → W6Cl12 + BiCl3 Unbalanced

(a) Balance the equation.

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