Ka and Kb
17. Acid and Base Equilibrium / Ka and Kb / Problem 4
Alanine is an amino acid that can have both equilibria in water:
H2N⎯CHCH3⎯COOH + H2O ⇌ +H3N⎯CHCH3⎯COOH + OH- Kb = 7.4x10−5
H2N⎯CHCH3⎯COOH + H2O ⇌ H2N⎯CHCH3⎯COO- + H3O+ Ka = 4.5×10−3
It forms a zwitterion by intramolecular proton transfer
H2N⎯CHCH3⎯COOH ⇌ +H3N⎯CHCH3⎯COO-
Determine the equilibrium constant for the reaction using the given Ka and Kb values
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