Most of the proteins that enter the nucleus possess a nuclear localization signal (NLS), even if they are small enough to pass through the nuclear pore complex unhindered. Why would a small protein have an NLS, when it naturally diffuses across the nuclear pore complex without one?

Video transcript

Hello everyone here. We have a question asking us which of the following states the importance of nuclear localization signal and transporting cargo proteins, cargo proteins are transported in the presence of a nuclear localization signal. This nuclear localization signal is recognized by the corresponding nuclear transporters. These nuclear transporters interact with nuclear peron's, helping the nuclear localization signal containing proteins reach the nucleus through the nuclear pore complex. So our answer here is a it helps the proteins reach the nucleus through the nuclear pore complex. Thank you for watching. Bye.