Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to a. disruption of mitotic spindle formation. b. suppression of cyclin production. c. myosin denaturation and inhibition of cleavage furrow formation. d.inhibition of DNA synthesis.
Ch. 12 - The Cell Cycle
Chapter 12, Problem 1
Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely a. an animal cell in the process of cytokinesis. b. a plant cell in the process of cytokinesis. c. a bacterial cell dividing. d. a plant cell in metaphase.
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Identify the key features described: a cell plate developing across the middle of a cell and nuclei forming on either side of the cell plate.
Recall that the cell plate is a structure that forms during cytokinesis in plant cells, which eventually leads to the formation of a new cell wall separating the two daughter cells.
Understand that animal cells do not form a cell plate; instead, they undergo cytokinesis by a process called cleavage, forming a cleavage furrow that pinches the cell into two.
Recognize that bacterial cells divide by binary fission, which does not involve the formation of a cell plate.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Cytokinesis
Cytokinesis is the process during cell division where the cytoplasm of a parental cell is divided into two daughter cells. In animal cells, this occurs through the formation of a cleavage furrow, while in plant cells, a cell plate forms to separate the two new cells. Understanding this process is crucial for identifying the type of cell division occurring in the question.
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Cell Plate Formation
The cell plate is a structure that forms during cytokinesis in plant cells, arising from vesicles that coalesce at the center of the cell. This plate eventually develops into the new cell wall that separates the two daughter cells. Recognizing the significance of the cell plate helps differentiate plant cell division from that of animal cells.
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Nuclear Division
Nuclear division, or mitosis, is the process where a cell's nucleus divides to ensure that each daughter cell receives an identical set of chromosomes. The presence of nuclei forming on either side of the cell plate indicates that mitosis has occurred prior to cytokinesis, which is a key detail in determining the type of cell involved in the question.
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Related Practice
Textbook Question
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Textbook Question
One difference between cancer cells and normal cells is that cancer cells a. are unable to synthesize DNA. b. are arrested at the S phase of the cell cycle. c. continue to divide even when they are tightly packed together. d. cannot function properly because they are affected by density-dependent inhibition.
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Textbook Question
The decline of MPF activity at the end of mitosis is due to a. the destruction of the protein kinase Cdk. b. decreased synthesis of Cdk. c. the degradation of cyclin. d. the accumulation of cyclin.
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